Back in Pharmacy School, I was taught that the drug Tramad0l, is a narcotic drug i.e a drug that can blunt your senses and for this, having side effects that can lead to dependence and ultimately abuse. Therefore making it a prescription drug in some countries - but not in Nigeria.
My experience working in community pharmacies has however opened my eyes to other "street uses" of "Trams" as it is popular called. I noticed that more men request for this drug more than women and even at a higher doses. Initially, I believed they were taking the drugs for its side effect -the euphoric feeling but with more clerking, some men actually told me they use to enhance their sex performance. I can remember being wawu'ed and wonder how people get to know the off label uses of these drugs. So since then, I have been researching on Trams and it association with sexual performance...
...and yes. Trams has shown efficacy in Premature ejaculation.
Premature ejaculation (PME) is defined as ejaculation with the minimal sexual stimulation before, on or shortly after penetration and or before a person wishes it.
Although the mechanism by which Tramad0l delays ejaculation has not been elucidated, most of the patients included in the studies reported that the drug reduced penile sensitivity, especially the gland penis. The sex life of patients improved and they reported greater satisfaction with the sporadic treatment.
However, there are many considerations on the use of tramadol. First, the long-term use can result in drug addiction, difficulty in breathing and the beneficial effect of tramadol in PME is yet not supported by a high level of evidence. In addition, despite its advantage for management of PME, Tramad0l can induce Erectile dysfunction as a side effect. This should be kept in mind. Before usage, it is required to carefully investigate the risk and benefit for each patient.
Adverse reactions of therapeutic use of tramad0l include nausea and dizziness, drowsiness, fatigue, headache, increased sweating, vomiting, dry mouth, constipation.
Tramadol is abused for its calming and euphoric effects. People who abuse tramadol usually feel relaxed and happy. Misuse of this drug can cause dependence, addiction, or death especially in a child or other person using the medicine without a prescription. A study from 2005 found that 84 percent of patients who abused tramadol in very high doses had seizures within 24 hours.
Take Tramad0l exactly as prescribed. Follow all directions on your prescription label. Tramad0l can slow or stop your breathing, especially when you start using this medicine or whenever your dose is changed. Never take this medicine in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in relieving your pain.
Have a World Cup fever-filled Sunday.
Pharm G B. IDAMKUE

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